Effectiveness of medical expulsive therapy with the ɲ-adrenergic blocker tamsulosin for distal ureterolithiasis in adults attended in an emergency department in Chile
Astroza Eulufi G, Sarrás Jadue M, Bettancourt Guglielmetti C, Lara Hernandez B, Neira Soto R, Aguilera Fuenzalida P
Affiliation of the authors
Departamento de Urología, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile. Servicio de Urgencias, Hospital Clínico, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile.
Astroza Eulufi G, Sarrás Jadue M, Bettancourt Guglielmetti C, Lara Hernandez B, Neira Soto R, Aguilera Fuenzalida P. Effectiveness of medical expulsive therapy with the ɲ-adrenergic blocker tamsulosin for distal ureterolithiasis in adults attended in an emergency department in Chile. Emergencias. 2019;31:404-6
To assess the effectiveness of medical expulsive therapy with tamsulosin.
Methods.
Randomized double-blind controlled trial in an emergency department. We enrolled adults with uncomplicated distal ureterolithiasis and no other complaint. Patients were randomized to take either tamsulosin (0.4 mg/d) plus a nonsteroidal anti-inflammatory drug (NSAID) or placebo plus the NSAID for 21 days.
Results.
The stone expulsion rate did not differ statistically between the 2 groups (P=.29). Time until expulsion was also similar (P=.91).
Conclusion. Medical expulsive therapy with tamsulosin does not improve the rate of distal ureteral stone expulsion
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