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Acute street drug poisoning in the patient with human immunodeficiency virus infection: the role of chemsex

Perelló R, Aused M, Saubí N, Quirós C, Blanco JL, Martínez-Rebollar M, Galicia M, Salgado E, Nogué S

√Ārea de Urgencias, Hospital Cl√≠nic, Barcelona, Spain. Servicio de Infecciones, Hospital Cl√≠nic, Barcelona, Spain.

Objective. To identify the drugs usually abused in cases of acute poisoning in human immunodeficiency virus (HIV)
infected patients.
Methods. Retrospective study of episodes of acute street drug poisoning in HIV-infected patients in our emergency department over a period of 1 year. Chemsex was defined as the use of methamphetamines, ????-hydroxybutyrate
(GHB), ????-butyrolactone (GBL), and/or mephedrone in order to prolong sexual activity.
Results. We included 101 patients, 93 (92%) of whom were men. The drug that caused the most cases of acute poisoning was cocaine, detected in 52 patients (51%). GHB and amphetamines were the next most frequently implicated street drugs. The prevalence of chemsex in this series was 87%. Mortality was 2%. Amphetamine poisoning was related to intensive care unit admission (odds ratio, 9,2 [95% CI, 1.6‚Äď52.2], P=.012).
Conclusion. Cocaine use was the main cause of acute poisoning in this series. The prevalence of chemsex was high.

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