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Nebulized furosemide to treat breathlessness in emergency patients with advanced cancer




Qui√Īones P√©rez A, √Ālvarez Jim√©nez P, Garc√≠a S√°nchez MJ, Ferrer Fr√≠as MM



Unidad de Gesti√≥n Cl√≠nica de Cuidados Cr√≠ticos y Urgencias. Equipo de Soporte de Cuidados Paliativos. Unidad de Gesti√≥n Cl√≠nica del Bloque Quir√ļrgico. √Ārea de Gesti√≥n Sanitaria Sur de Granada. Motril. Granada, Spain.



Three patients with advanced cancer and acute dyspnea for different reasons were
treated with furosemide spray in a hospital emergency department. A single dose of 40
mg of nebulized furosemide was sprayed and inhaled in a single dose. Breathlessness
improved significantly, bringing the episode under control, in patients with at least 50%
of function according to the Palliative Performance Status (PPS) scale. However,
furosemide did not improve the condition of a patient with end-stage dyspnea. No
adverse effects were observed. Inhaling nebulized furosemide seems to be an effective
treatment for breathlessness in patients with terminal cancer and a 50% PPS function
assessment, although randomized controlled trials are needed to confirm this
hypothesis.


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